Across TCGA patient cohorts, TYW1 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,287 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TYW1-associated proteins across cancer lineages are ZKSCAN1, RSBN1L, and EIF4H. Each is linked with TYW1 in more than 7 cancer types. Because this analysis shows association rather than direction, both TYW1-to-partner and partner-to-TYW1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TYW1→partner) and Y-score (partner→TYW1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	ZKSCAN1 →	+0.458	+0.296	.001	.003	3	8
GBM	RSBN1L →	+0.293	+0.362	<.001	<.001	3	7
COAD	EIF4H →	+0.290	+0.349	<.001	<.001	3	7
HNSC	GTF2I →	+0.423	+0.575	.001	.001	2	8
LSCC	MEPCE →	+0.301	+0.520	<.001	<.001	3	7
BRCA	YWHAG →	+0.328	+0.371	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,287 associations by consensus.

Exploration

TYW1 survival (RNA) · tumor vs normal (RNA) · all TYW1 data types