Across TCGA patient cohorts, TYW1 protein abundance is significantly associated with the protein abundance of many other proteins, with 9,095 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TYW1-associated proteins across cancer lineages are TBL2, CANX, and DPM3. Each is linked with TYW1 in more than 5 cancer types. Because this analysis shows association rather than direction, both TYW1-to-partner and partner-to-TYW1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TYW1→partner) and Y-score (partner→TYW1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	TBL2 →	+0.463	+0.541	<.001	<.001	3	6
UCEC	CANX →	+0.953	+0.602	<.001	<.001	3	4
UCEC	DPM3 →	+0.771	+0.446	<.001	<.001	3	4
BRCA	NCLN →	+0.390	+0.474	<.001	<.001	3	4
UCEC	TOR1AIP2 →	+0.619	+0.517	<.001	<.001	3	4
UCEC	NSDHL →	+0.419	+0.536	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,095 associations by consensus.

Exploration

TYW1 survival (RNA) · tumor vs normal (RNA) · all TYW1 data types