TYW1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TYW1 mutation is significantly associated with the RNA expression of many other genes, with 2,263 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TYW1-associated genes across cancer lineages are MIR6737, ZP4, and MIR8075. Each is linked with TYW1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TYW1-to-partner and partner-to-TYW1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TYW1→partner) and Y-score (partner→TYW1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCAMIR6737 →+0.346+4.506<.001.00932
SCLCZP4 →+0.425+4.847<.001.00932
BRCAMIR8075 →+0.485+7.027<.001<.00132
UCECSLC25A4 →+0.597+2.273<.001<.00132
UCECMPPE1 →+0.426+2.130<.001.00232
UCECABHD3 →+0.689+3.108<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,263 associations by consensus.

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