Across TCGA cell cohorts, TYW1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,236 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TYW1-associated GO terms across cancer lineages are Positive regulation of isotype switching to IgG isotypes, Peptidyl-glutamic acid carboxylation, and Protein carboxylation. Each is linked with TYW1 in more than 15 cancer types. Because this analysis shows association rather than direction, both TYW1-to-partner and partner-to-TYW1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TYW1→partner) and Y-score (partner→TYW1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Positive regulation of isotype switching to IgG isotypes →	+0.165	+1.012	<.001	<.001	3	16
OESOPHAGUS	Peptidyl-glutamic acid carboxylation →	+0.157	+0.821	<.001	<.001	3	13
OESOPHAGUS	Protein carboxylation →	+0.157	+0.821	<.001	<.001	3	13
LARGE_INTESTINE	Pre-mRNA catabolic process →	+0.137	+0.502	<.001	<.001	3	12
OESOPHAGUS	Cytosolic ribosome assembly →	+0.111	+0.771	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Regulation of isotype switching to IgG isotypes →	+0.120	+0.868	<.001	.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,236 associations by consensus.

Exploration

TYW1 survival (RNA) · tumor vs normal (RNA) · all TYW1 data types