TYRO3P

Across TCGA pan-cancer cohorts, TYRO3P RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of TYRO3P’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where TYRO3P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TYRO3P is over-expressed in tumor.

COAD, STAD, and KICH are the cancer types where TYRO3P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TYRO3P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	All	+0.056	.007	5	view →
STAD	All	II,III,IV	+0.201	.026	3	view →
KICH	Female	II,III,IV	+0.054	.003	3	view →
BLCA	Female	III,IV	+0.077	.003	2	view →
CHOL	All	All	+0.074	.024	2	view →
KIRC	Female	All	+0.039	.044	2	view →
ESCA	Female	All	+0.186	.040	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

TYRO3P–COAD

Open the COAD breakdown →