TYR

Across TCGA patient cohorts, TYR protein abundance is significantly associated with the go_rna of many other GO terms, with 16 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible TYR-associated GO terms across cancer lineages are Positive regulation of viral life cycle, Subpallium development, and Endothelial cell fate commitment. Each is linked with TYR in more than 1 cancer types. Because this analysis shows association rather than direction, both TYR-to-partner and partner-to-TYR results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of viral life cycle grouped by TYR-low versus TYR-high in CCRCC.

protein abundance associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TYR→partner) and Y-score (partner→TYR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	Positive regulation of viral life cycle →	-0.097	-0.864	.009	.009	3	1
CCRCC	Subpallium development →	-0.084	-0.506	.009	.004	3	1
CCRCC	Endothelial cell fate commitment →	+0.154	+0.484	.002	.006	3	1
CCRCC	Telomeric loop disassembly →	-0.089	-0.565	.007	.008	2	1
CCRCC	Negative regulation of leukocyte chemotaxis →	+0.150	+0.584	<.001	.004	2	1
CCRCC	Negative regulation of axon extension →	+0.063	+0.530	.002	.004	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

Positive regulation of viral life cycle by TYR expression — CCRCC

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