TYR

Across TCGA cell cohorts, TYR RNA expression is significantly associated with the go_rna of many other GO terms, with 3,100 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible TYR-associated GO terms across cancer lineages are Response to anesthetic, Neutrophil-mediated killing of fungus, and Response to dehydroepiandrosterone. Each is linked with TYR in more than 9 cancer types. Because this analysis shows association rather than direction, both TYR-to-partner and partner-to-TYR results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to anesthetic grouped by TYR-low versus TYR-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TYR→partner) and Y-score (partner→TYR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Response to anesthetic →	-0.116	-0.129	<.001	.006	3	10
URINARY_TRACT	Neutrophil-mediated killing of fungus →	+0.192	+0.146	<.001	.002	3	9
SOFT_TISSUE	Response to dehydroepiandrosterone →	+0.192	+0.064	<.001	.002	3	8
SOFT_TISSUE	Metaphase/anaphase transition of mitotic cell cycle →	+0.125	+0.041	<.001	.002	3	7
BONE	Regulation of iron ion import across plasma membrane →	-0.209	-0.083	<.001	<.001	3	7
BONE	Positive regulation of intracellular estrogen receptor signaling pathway →	+0.148	+0.062	.003	.002	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,100 associations by consensus.

Response to anesthetic by TYR expression — URINARY_TRACT

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