TYMSP2

Across TCGA patient cohorts, TYMSP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,416 significant associations in total. STAD shows the largest number of these associations.

The most reproducible TYMSP2-associated GO terms across cancer lineages are Negative regulation of DNA-templated transcription, elongation, tRNA metabolic process, and Mitochondrial translation. Each is linked with TYMSP2 in more than 14 cancer types. Because this analysis shows association rather than direction, both TYMSP2-to-partner and partner-to-TYMSP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of DNA-templated transcription, elongation grouped by TYMSP2-low versus TYMSP2-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TYMSP2→partner) and Y-score (partner→TYMSP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Negative regulation of DNA-templated transcription, elongation →	+0.071	+0.194	<.001	<.001	3	15
STAD	tRNA metabolic process →	+0.068	+0.197	<.001	<.001	3	15
STAD	Mitochondrial translation →	+0.081	+0.194	<.001	<.001	3	14
STAD	Protein insertion into mitochondrial inner membrane →	+0.066	+0.198	<.001	<.001	3	14
STAD	Positive regulation of DNA repair →	+0.062	+0.213	<.001	<.001	3	14
STAD	Base-excision repair →	+0.064	+0.192	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,416 associations by consensus.

Negative regulation of DNA-templated transcription, elongation by TYMSP2 expression — STAD

Explore this box plot interactively →