Across TCGA patient cohorts, TXNRD3 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,655 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TXNRD3-associated proteins across cancer lineages are GMPS, TXNRD3_S42, and DBR1. Each is linked with TXNRD3 in more than 5 cancer types. Because this analysis shows association rather than direction, both TXNRD3-to-partner and partner-to-TXNRD3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TXNRD3→partner) and Y-score (partner→TXNRD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	GMPS →	+0.382	+0.655	<.001	<.001	3	6
LSCC	TXNRD3_S42 →	+0.761	+0.683	<.001	<.001	3	6
LSCC	DBR1 →	+0.280	+0.663	<.001	<.001	3	5
LSCC	HMCES →	+0.471	+0.793	<.001	<.001	3	5
CCRCC	EEFSEC →	+0.232	+0.408	<.001	<.001	3	5
LSCC	FUS →	+0.452	+0.758	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,655 associations by consensus.

Exploration

TXNRD3 survival (RNA) · tumor vs normal (RNA) · all TXNRD3 data types