Across TCGA patient cohorts, TXNRD3 protein abundance is significantly associated with the RNA expression of many other genes, with 8,544 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TXNRD3-associated genes across cancer lineages are H2BC14, SLC25A36, and NMNAT3. Each is linked with TXNRD3 in more than 3 cancer types. Because this analysis shows association rather than direction, both TXNRD3-to-partner and partner-to-TXNRD3 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TXNRD3→partner) and Y-score (partner→TXNRD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	H2BC14 →	-1.654	-0.492	<.001	<.001	3	4
LSCC	SLC25A36 →	+0.982	+0.398	<.001	<.001	3	4
LSCC	NMNAT3 →	+0.878	+0.421	<.001	<.001	3	4
HNSC	FTCDNL1 →	+0.669	+0.313	<.001	.006	3	4
GBM	CENPE →	-0.802	-0.251	<.001	.005	3	3
LSCC	PRDX6 →	+0.420	+0.274	.002	.006	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,544 associations by consensus.

Exploration

TXNRD3 survival (RNA) · tumor vs normal (RNA) · all TXNRD3 data types