Across TCGA patient cohorts, TXNRD2 protein abundance is significantly associated with the RNA expression of many other genes, with 6,828 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible TXNRD2-associated genes across cancer lineages are HAPLN3, MLPH, and SYBU. Each is linked with TXNRD2 in more than 4 cancer types. Because this analysis shows association rather than direction, both TXNRD2-to-partner and partner-to-TXNRD2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TXNRD2→partner) and Y-score (partner→TXNRD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	HAPLN3 →	-0.984	-0.372	<.001	<.001	3	5
BRCA	MLPH →	+2.133	+0.497	<.001	<.001	3	4
BRCA	SYBU →	+1.267	+0.466	<.001	<.001	3	4
BRCA	CALB2 →	-1.662	-0.459	<.001	<.001	3	4
HNSC	TUBB6 →	-0.947	-0.279	<.001	<.001	3	4
HNSC	MT-ND4L →	+1.478	+0.196	<.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,828 associations by consensus.

Exploration

TXNRD2 survival (RNA) · tumor vs normal (RNA) · all TXNRD2 data types