Across TCGA patient cohorts, TXNRD1 protein abundance is significantly associated with the RNA expression of many other genes, with 13,042 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TXNRD1-associated genes across cancer lineages are NQO1, EID3, and PIR. Each is linked with TXNRD1 in more than 6 cancer types. Because this analysis shows association rather than direction, both TXNRD1-to-partner and partner-to-TXNRD1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TXNRD1→partner) and Y-score (partner→TXNRD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	NQO1 →	+2.416	+0.911	<.001	<.001	3	7
LSCC	EID3 →	+2.315	+1.047	<.001	<.001	3	7
LSCC	PIR →	+1.215	+0.609	<.001	<.001	3	7
LSCC	NMRAL2P →	+4.216	+0.868	<.001	<.001	3	6
LSCC	AKR1B10 →	+3.471	+0.836	<.001	<.001	3	6
LSCC	TALDO1 →	+1.239	+0.916	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,042 associations by consensus.

Exploration

TXNRD1 survival (RNA) · tumor vs normal (RNA) · all TXNRD1 data types