Across TCGA patient cohorts, TXNRD1 mutation is significantly associated with the RNA expression of many other genes, with 5,051 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TXNRD1-associated genes across cancer lineages are RPS27P18, RNU7-56P, and TUBB4BP6. Each is linked with TXNRD1 in more than 2 cancer types. Because this analysis shows association rather than direction, both TXNRD1-to-partner and partner-to-TXNRD1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TXNRD1→partner) and Y-score (partner→TXNRD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RPS27P18 →	+0.125	+4.342	<.001	.007	3	3
PRAD	RNU7-56P →	+0.503	+6.593	<.001	.001	3	3
SKCM	TUBB4BP6 →	+0.034	+4.039	<.001	.009	3	3
LUAD	RNU6-1290P →	+0.333	+4.712	<.001	.007	3	3
UCEC	TMEM87A →	+0.402	+1.671	.001	.007	3	3
UCEC	EIF3J →	+0.609	+2.857	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,051 associations by consensus.

Exploration

TXNRD1 survival (RNA) · tumor vs normal (RNA) · all TXNRD1 data types