TXNP6

Across TCGA pan-cancer cohorts, TXNP6 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of TXNP6’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where TXNP6 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TXNP6 is over-expressed in tumor.

COAD, LIHC, and LUAD are the cancer types where TXNP6 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TXNP6 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Female	All	+1.427	<.001	8	view →
LIHC	All	II,III,IV	+0.364	<.001	8	view →
LUAD	All	All	+0.643	<.001	7	view →
LUSC	All	All	+0.319	<.001	6	view →
UCEC	All	All	+0.701	.020	4	view →
BRCA	All	All	+0.251	.002	4	view →
PRAD	All	All	+0.286	.003	2	view →
CHOL	All	II,III,IV	+0.265	.010	2	view →
READ	All	All	+0.681	.016	1	view →
BLCA	All	III,IV	+0.675	.017	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

TXNP6–COAD

Open the COAD breakdown →