TXNP1

Across TCGA pan-cancer cohorts, TXNP1 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of TXNP1’s most consistent transcriptional readouts.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where TXNP1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TXNP1 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

BLCA, LUSC, and PRAD are the cancer types where TXNP1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TXNP1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BLCA	Male	All	+0.118	.042	2	view →
LUSC	All	All	+0.099	.025	2	view →
PRAD	All	All	+0.076	.027	2	view →
THCA	All	IV	−0.145	.028	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

TXNP1–BLCA

Open the BLCA breakdown →