TXNDC9

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TXNDC9 mutation is significantly associated with the total protein of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TXNDC9-associated genes across cancer lineages are N-Ras and SF2. Each is linked with TXNDC9 in more than 1 cancer types. Because this analysis shows association rather than direction, both TXNDC9-to-partner and partner-to-TXNDC9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, N-Ras grouped by TXNDC9-low versus TXNDC9-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TXNDC9→partner) and Y-score (partner→TXNDC9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECN-Ras →+0.229+2.820.001.03631
UCECSF2 →+0.133+2.820.047.03621
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

N-Ras by TXNDC9 expression — UCEC

Box plot of N-Ras in TXNDC9-low vs TXNDC9-high samples in UCEC.

Explore this box plot interactively →

Exploration