TXNDC9

Across TCGA cell cohorts, TXNDC9 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,619 significant associations in total. BONE shows the largest number of these associations.

The most reproducible TXNDC9-associated GO terms across cancer lineages are Centromeric sister chromatid cohesion, Positive regulation of chromosome condensation, and Negative regulation of metaphase/anaphase transition of cell cycle. Each is linked with TXNDC9 in more than 12 cancer types. Because this analysis shows association rather than direction, both TXNDC9-to-partner and partner-to-TXNDC9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Centromeric sister chromatid cohesion grouped by TXNDC9-low versus TXNDC9-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TXNDC9→partner) and Y-score (partner→TXNDC9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Centromeric sister chromatid cohesion →	+0.133	+0.469	<.001	.001	3	13
LUNG_NSCLC_LUSC	Positive regulation of chromosome condensation →	+0.189	+0.554	.004	.005	3	13
BLOOD_Lymphoma	Negative regulation of metaphase/anaphase transition of cell cycle →	+0.109	+0.762	<.001	<.001	3	13
BLOOD_Lymphoma	Spindle checkpoint signaling →	+0.107	+0.736	<.001	.001	3	13
BLOOD_Lymphoma	Negative regulation of chromosome separation →	+0.109	+0.762	<.001	<.001	3	13
BREAST	Regulation of chromosome segregation →	+0.095	+0.590	.002	.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,619 associations by consensus.

Centromeric sister chromatid cohesion by TXNDC9 expression — SOFT_TISSUE

Explore this box plot interactively →