TXNDC5

Across TCGA cell cohorts, TXNDC5 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,374 significant associations in total. BONE shows the largest number of these associations.

The most reproducible TXNDC5-associated GO terms across cancer lineages are Glycoprotein biosynthetic process, Multi-pass transmembrane protein insertion into ER membrane, and Regulation of protein exit from endoplasmic reticulum. Each is linked with TXNDC5 in more than 15 cancer types. Because this analysis shows association rather than direction, both TXNDC5-to-partner and partner-to-TXNDC5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Glycoprotein biosynthetic process grouped by TXNDC5-low versus TXNDC5-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TXNDC5→partner) and Y-score (partner→TXNDC5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Glycoprotein biosynthetic process →	+0.061	+1.134	<.001	<.001	3	16
LIVER	Multi-pass transmembrane protein insertion into ER membrane →	+0.169	+1.217	<.001	.006	3	15
BONE	Regulation of protein exit from endoplasmic reticulum →	+0.119	+1.006	<.001	<.001	3	14
BONE	Protein N-linked glycosylation →	+0.106	+1.567	<.001	<.001	3	12
BREAST	Positive regulation of protein exit from endoplasmic reticulum →	+0.125	+1.041	<.001	<.001	3	12
BONE	COPII-coated vesicle cargo loading →	+0.117	+1.162	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,374 associations by consensus.

Glycoprotein biosynthetic process by TXNDC5 expression — SOFT_TISSUE

Explore this box plot interactively →