TXNDC2

Across TCGA patient cohorts, TXNDC2 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,138 significant associations in total. STAD shows the largest number of these associations.

The most reproducible TXNDC2-associated GO terms across cancer lineages are Cell-matrix adhesion, Integrin-mediated signaling pathway, and Branching involved in blood vessel morphogenesis. Each is linked with TXNDC2 in more than 21 cancer types. Because this analysis shows association rather than direction, both TXNDC2-to-partner and partner-to-TXNDC2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cell-matrix adhesion grouped by TXNDC2-low versus TXNDC2-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TXNDC2→partner) and Y-score (partner→TXNDC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Cell-matrix adhesion →	+0.073	+0.176	<.001	<.001	3	22
STAD	Integrin-mediated signaling pathway →	+0.088	+0.185	<.001	<.001	3	22
STAD	Branching involved in blood vessel morphogenesis →	+0.085	+0.171	<.001	<.001	3	22
STAD	Cell adhesion mediated by integrin →	+0.076	+0.163	<.001	<.001	3	22
STAD	Artery morphogenesis →	+0.070	+0.164	<.001	<.001	3	22
ESCA	Aorta development →	+0.069	+0.214	<.001	<.001	3	22

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,138 associations by consensus.

Cell-matrix adhesion by TXNDC2 expression — STAD

Explore this box plot interactively →