TXNDC16

Across TCGA patient cohorts, TXNDC16 protein abundance is significantly associated with the RNA expression of many other genes, with 6,504 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TXNDC16-associated genes across cancer lineages are VRK1, CSE1L, and PCNA. Each is linked with TXNDC16 in more than 2 cancer types. Because this analysis shows association rather than direction, both TXNDC16-to-partner and partner-to-TXNDC16 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TXNDC16 versus VRK1 in LSCC, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TXNDC16→partner) and Y-score (partner→TXNDC16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	VRK1 →	+0.607	+0.360	<.001	<.001	3	3
OV	CSE1L →	+0.673	+1.052	.001	.002	3	3
LSCC	PCNA →	+0.748	+0.494	<.001	<.001	3	3
GBM	KIF15 →	+0.884	+0.353	.002	.002	3	3
GBM	FOXRED2 →	+0.590	+0.431	<.001	<.001	3	3
GBM	POLE2 →	+0.708	+0.440	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,504 associations by consensus.

TXNDC16 vs VRK1 — LSCC

Explore this scatter interactively →