TXNDC16

Across TCGA patient cohorts, TXNDC16 protein abundance is significantly associated with the protein abundance of many other proteins, with 15,358 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TXNDC16-associated proteins across cancer lineages are WDHD1_S407, WEE1_T190, and ZNF219. Each is linked with TXNDC16 in more than 3 cancer types. Because this analysis shows association rather than direction, both TXNDC16-to-partner and partner-to-TXNDC16 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TXNDC16 versus WDHD1_S407 in GBM, with a Pearson correlation of 0.47.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TXNDC16→partner) and Y-score (partner→TXNDC16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	WDHD1_S407 →	+1.016	+0.542	<.001	<.001	3	3
LUAD	WEE1_T190 →	+0.893	+0.484	.002	.003	3	3
LSCC	ZNF219 →	+0.671	+0.488	<.001	.002	3	3
LSCC	RCC2 →	+0.582	+0.623	<.001	<.001	3	3
GBM	SNRPA →	+0.286	+0.467	<.001	.004	3	3
GBM	TFDP1_S23 →	+0.802	+0.426	<.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,358 associations by consensus.

TXNDC16 vs WDHD1_S407 — GBM

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