TXNDC16

Across TCGA cell cohorts, TXNDC16 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,688 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TXNDC16-associated GO terms across cancer lineages are Positive regulation of stem cell population maintenance, Negative regulation of cell cycle G2/M phase transition, and Negative regulation of cell cycle process. Each is linked with TXNDC16 in more than 13 cancer types. Because this analysis shows association rather than direction, both TXNDC16-to-partner and partner-to-TXNDC16 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of stem cell population maintenance grouped by TXNDC16-low versus TXNDC16-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TXNDC16→partner) and Y-score (partner→TXNDC16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Positive regulation of stem cell population maintenance →	+0.084	+1.046	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Negative regulation of cell cycle G2/M phase transition →	+0.087	+0.944	.002	<.001	3	14
OESOPHAGUS	Negative regulation of cell cycle process →	+0.082	+1.323	.004	.003	3	14
LUNG_NSCLC_LUSC	Regulation of nucleotide-excision repair →	+0.116	+1.117	<.001	.001	3	13
LUNG_SCLC	Epigenetic regulation of gene expression →	+0.060	+1.398	.002	.003	3	13
LUNG_NSCLC_LUSC	Sister chromatid cohesion →	+0.120	+1.405	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,688 associations by consensus.

Positive regulation of stem cell population maintenance by TXNDC16 expression — LUNG_SCLC

Explore this box plot interactively →