TXNDC15

Across TCGA pan-cancer cohorts, TXNDC15 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated TXNDC15 data layer compared with 27 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher TXNDC15 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated TXNDC15 expression acts as an unfavorable survival marker.

PDAC, OV, and UCEC are the cancer types where TXNDC15 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	DFS	Median	All	0.190	0.683	.005	22	view →
OV	DFS	Median	All	0.867	1.000	.035	8	view →
UCEC	DFS	Median	All	0.868	1.000	.005	6	view →
LUAD	DFS	Quartile	III,IV	0.608	0.910	.044	3	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

TXNDC15–PDAC (DFS)

Open the PDAC breakdown →