TXNDC15

Across TCGA patient cohorts, TXNDC15 protein abundance is significantly associated with the RNA expression of many other genes, with 5,415 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TXNDC15-associated genes across cancer lineages are FCRL6, CRB3, and MYLK. Each is linked with TXNDC15 in more than 2 cancer types. Because this analysis shows association rather than direction, both TXNDC15-to-partner and partner-to-TXNDC15 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TXNDC15 versus FCRL6 in HNSC, with a Pearson correlation of -0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TXNDC15→partner) and Y-score (partner→TXNDC15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	FCRL6 →	-0.781	-0.268	.009	.005	3	3
UCEC	CRB3 →	-0.931	-0.315	.007	.008	3	3
UCEC	MYLK →	-0.855	-0.457	.004	.002	3	3
UCEC	B9D2 →	-1.061	-0.435	<.001	.001	3	2
HNSC	APOE →	-1.484	-0.231	.001	.004	2	3
OV	GNG5P2 →	+1.617	+0.204	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,415 associations by consensus.

TXNDC15 vs FCRL6 — HNSC

Explore this scatter interactively →