TXNDC15

Across TCGA cell cohorts, TXNDC15 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,684 significant associations in total. BONE shows the largest number of these associations.

The most reproducible TXNDC15-associated GO terms across cancer lineages are Vesicle cargo loading, Positive regulation of protein exit from endoplasmic reticulum, and Regulation of protein exit from endoplasmic reticulum. Each is linked with TXNDC15 in more than 13 cancer types. Because this analysis shows association rather than direction, both TXNDC15-to-partner and partner-to-TXNDC15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Vesicle cargo loading grouped by TXNDC15-low versus TXNDC15-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TXNDC15→partner) and Y-score (partner→TXNDC15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Vesicle cargo loading →	+0.163	+1.228	<.001	.001	3	14
STOMACH	Positive regulation of protein exit from endoplasmic reticulum →	+0.141	+1.150	<.001	.001	3	14
BONE	Regulation of protein exit from endoplasmic reticulum →	+0.123	+0.936	<.001	<.001	3	12
BLOOD_Myeloma	Positive regulation of retrograde protein transport, ER to cytosol →	+0.170	+1.113	.003	.007	3	12
BONE	Collagen fibril organization →	+0.290	+0.906	<.001	<.001	3	12
BLOOD_Myeloma	ERAD pathway →	+0.099	+1.141	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,684 associations by consensus.

Vesicle cargo loading by TXNDC15 expression — BONE

Explore this box plot interactively →