TXNDC11

Across TCGA pan-cancer cohorts, TXNDC11 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated TXNDC11 data layer compared with 27 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher TXNDC11 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated TXNDC11 expression acts as an unfavorable survival marker, although some lineages such as LUAD and HNSC show a favorable association.

LUAD, PDAC, and CCRCC are the cancer types where TXNDC11 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Tertile	All	1.000	0.717	.012	10	view →
PDAC	OS	Quartile	II,III,IV	0.421	0.758	.021	8	view →
CCRCC	DFS	Quartile	III,IV	0.184	0.881	.005	7	view →
HNSC	DFS	Quartile	All	0.860	0.215	.024	6	view →
UCEC	DFS	Median	All	0.853	0.950	.034	2	view →
GBM	DFS	Quartile	All	0.528	0.884	.048	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

TXNDC11–LUAD (OS)

Open the LUAD breakdown →