TXNDC11

Across TCGA patient cohorts, TXNDC11 protein abundance is significantly associated with the RNA expression of many other genes, with 14,627 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TXNDC11-associated genes across cancer lineages are ZC3H8, DFFA, and COA8. Each is linked with TXNDC11 in more than 4 cancer types. Because this analysis shows association rather than direction, both TXNDC11-to-partner and partner-to-TXNDC11 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TXNDC11 versus ZC3H8 in LSCC, with a Pearson correlation of -0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TXNDC11→partner) and Y-score (partner→TXNDC11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ZC3H8 →	-0.433	-0.213	<.001	<.001	3	5
LSCC	DFFA →	-0.651	-0.345	<.001	<.001	3	5
LSCC	COA8 →	-0.402	-0.299	.001	<.001	3	5
LSCC	C1orf109 →	-0.610	-0.393	<.001	<.001	3	5
CCRCC	AIP →	-0.517	-0.546	<.001	<.001	3	4
OV	SLC25A26 →	-0.444	-0.349	.009	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,627 associations by consensus.

TXNDC11 vs ZC3H8 — LSCC

Explore this scatter interactively →