TXNDC11

Across TCGA cell cohorts, TXNDC11 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,736 significant associations in total. BONE shows the largest number of these associations.

The most reproducible TXNDC11-associated GO terms across cancer lineages are Protein exit from endoplasmic reticulum, Endoplasmic reticulum to cytosol transport, and Retrograde protein transport, ER to cytosol. Each is linked with TXNDC11 in more than 14 cancer types. Because this analysis shows association rather than direction, both TXNDC11-to-partner and partner-to-TXNDC11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein exit from endoplasmic reticulum grouped by TXNDC11-low versus TXNDC11-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TXNDC11→partner) and Y-score (partner→TXNDC11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Protein exit from endoplasmic reticulum →	+0.121	+0.572	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Endoplasmic reticulum to cytosol transport →	+0.134	+0.585	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Retrograde protein transport, ER to cytosol →	+0.134	+0.585	<.001	<.001	3	12
STOMACH	Cellular response to cold →	+0.138	+0.600	<.001	.002	3	12
LIVER	Negative regulation of IRE1-mediated unfolded protein response →	+0.119	+0.975	.001	.002	3	11
UPPER_AERODIGESTIVE_TRACT	Regulation of Golgi inheritance →	+0.168	+0.585	.002	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,736 associations by consensus.

Protein exit from endoplasmic reticulum by TXNDC11 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →