TXN2

Across TCGA cell cohorts, TXN2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,417 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TXN2-associated GO terms across cancer lineages are Positive regulation of mitochondrial fusion, Positive regulation of T-helper 17 cell lineage commitment, and Mitochondrial ribosome assembly. Each is linked with TXN2 in more than 11 cancer types. Because this analysis shows association rather than direction, both TXN2-to-partner and partner-to-TXN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of mitochondrial fusion grouped by TXN2-low versus TXN2-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TXN2→partner) and Y-score (partner→TXN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Positive regulation of mitochondrial fusion →	+0.152	+0.764	.001	<.001	3	12
URINARY_TRACT	Positive regulation of T-helper 17 cell lineage commitment →	+0.176	+0.890	<.001	<.001	3	12
BLOOD_Lymphoma	Mitochondrial ribosome assembly →	+0.110	+0.585	<.001	<.001	3	11
BLOOD_Lymphoma	Mitochondrial large ribosomal subunit assembly →	+0.111	+0.526	<.001	.001	3	11
URINARY_TRACT	Protein localization to microtubule plus-end →	+0.183	+1.017	<.001	<.001	3	11
URINARY_TRACT	Protein localization to microtubule end →	+0.183	+1.017	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,417 associations by consensus.

Positive regulation of mitochondrial fusion by TXN2 expression — PANCREAS

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