Across TCGA pan-cancer cohorts, TXLNG mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated TXLNG data layer compared with 25 for mass-spec protein and 1 for mutation status.
The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher TXLNG mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated TXLNG expression acts as an unfavorable survival marker, although some lineages such as UCEC and GBM show a favorable association.
UCEC, CCRCC, and HNSC are the cancer types where TXLNG mass-spec protein most reproducibly stratifies survival.