TXLNB

Across TCGA pan-cancer cohorts, TXLNB Mutation is linked to patient survival in 5 of 34 cancer types, making it a survival-associated TXLNB data layer compared with 24 for mass-spec protein and 2 for mass-spec protein.

The strongest signal is observed in testicular germ cell tumors (TGCT), where higher TXLNB Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated TXLNB expression acts as an unfavorable survival marker.

TGCT, BRCA, and HNSC are the cancer types where TXLNB Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
TGCT	OS	Median	III,IV	0.003	1.000	<.001	36	view →
BRCA	OS	Median	II,III,IV	0.103	0.565	.001	24	view →
HNSC	OS	Median	All	0.174	0.686	.001	12	view →
BLCA	OS	Median	IV	0.132	0.599	.004	6	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

TXLNB–TGCT (OS)

Open the TGCT breakdown →