TXLNA

Across TCGA pan-cancer cohorts, TXLNA mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated TXLNA data layer compared with 21 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher TXLNA mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated TXLNA expression acts as an unfavorable survival marker, although some lineages such as LUAD and UCEC show a favorable association.

CCRCC, HNSC, and LUAD are the cancer types where TXLNA mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Quartile	III,IV	0.457	0.940	.002	26	view →
HNSC	DFS	Quartile	All	0.152	0.771	.017	17	view →
LUAD	OS	Quartile	III,IV	1.000	0.278	.031	4	view →
GBM	DFS	Median	All	0.672	0.827	.023	2	view →
UCEC	DFS	Quartile	All	0.966	0.769	.049	2	view →
PDAC	DFS	Median	All	0.724	0.859	.031	1	view →
LSCC	DFS	Median	All	0.879	0.529	.046	1	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

TXLNA–CCRCC (OS)

Open the CCRCC breakdown →