TXLNA

Across TCGA patient cohorts, TXLNA RNA expression is significantly associated with the mutation status of many other genes, with 10,646 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TXLNA-associated genes across cancer lineages are TTN, UBR4, and FRAS1. Each is linked with TXLNA in more than 5 cancer types. Because this analysis shows association rather than direction, both TXLNA-to-partner and partner-to-TXLNA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TTN grouped by TXLNA-low versus TXLNA-high in LGG.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TXLNA→partner) and Y-score (partner→TXLNA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LGG	TTN →	+1.239	+0.250	.006	.006	2	6
COAD	UBR4 →	+2.235	+0.423	<.001	<.001	3	5
COAD	FRAS1 →	+2.598	+0.342	<.001	<.001	3	5
COAD	TENM3 →	+2.255	+0.295	<.001	<.001	3	5
COAD	DOCK2 →	+4.141	+0.294	<.001	<.001	3	4
GBM	TP53 →	+2.321	+0.285	.002	.002	2	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,646 associations by consensus.

TTN by TXLNA expression — LGG

Explore this box plot interactively →