TXLNA

Across TCGA cell cohorts, TXLNA mutation is significantly associated with the RNA expression of many other genes, with 42 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TXLNA-associated genes across cancer lineages are MYOCOS, ST8SIA3, and KRTAP5-6. Each is linked with TXLNA in more than 1 cancer types. Because this analysis shows association rather than direction, both TXLNA-to-partner and partner-to-TXLNA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MYOCOS grouped by TXLNA-low versus TXLNA-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TXLNA→partner) and Y-score (partner→TXLNA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	MYOCOS →	+0.019	+3.920	.009	.005	3	1
BLOOD_Leukemia	ST8SIA3 →	+0.053	+4.551	<.001	.004	3	1
BLOOD_Leukemia	KRTAP5-6 →	+0.333	+4.874	<.001	.002	3	1
LARGE_INTESTINE	NDUFB10 →	+0.550	+3.067	.001	.009	3	1
LARGE_INTESTINE	METTL21A →	+0.702	+3.064	.003	.009	3	1
LARGE_INTESTINE	BANP →	+0.674	+3.067	.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 42 associations by consensus.

MYOCOS by TXLNA expression — SKIN

Explore this box plot interactively →