TWF2

Across TCGA pan-cancer cohorts, TWF2 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated TWF2 data layer compared with 23 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher TWF2 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated TWF2 expression acts as an unfavorable survival marker.

CCRCC, PDAC, and COAD are the cancer types where TWF2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Median	All	0.849	0.981	.001	13	view →
PDAC	OS	Median	IV	0.540	0.951	.017	12	view →
COAD	DFS	Tertile	All	0.864	1.000	.038	12	view →
LSCC	OS	Quartile	II,III,IV	0.512	0.938	.005	12	view →
GBM	OS	Median	All	0.797	0.914	.034	4	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

TWF2–CCRCC (DFS)

Open the CCRCC breakdown →