TWF2

Across TCGA patient cohorts, TWF2 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,581 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TWF2-associated proteins across cancer lineages are PLEKHO2, DPYD, and ARPC5. Each is linked with TWF2 in more than 5 cancer types. Because this analysis shows association rather than direction, both TWF2-to-partner and partner-to-TWF2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TWF2 versus PLEKHO2 in COAD, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TWF2→partner) and Y-score (partner→TWF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	PLEKHO2 →	+0.442	+0.548	<.001	<.001	3	6
GBM	DPYD →	+0.617	+0.262	<.001	<.001	3	6
LSCC	ARPC5 →	+0.275	+0.376	<.001	<.001	3	6
GBM	SPI1 →	+0.562	+0.318	<.001	<.001	3	5
CCRCC	VSIG4 →	+0.836	+0.408	<.001	<.001	3	5
GBM	WIPF1 →	+0.291	+0.309	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,581 associations by consensus.

TWF2 vs PLEKHO2 — COAD

Explore this scatter interactively →