TWF2

Across TCGA patient cohorts, TWF2 protein abundance is significantly associated with the RNA expression of many other genes, with 18,668 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TWF2-associated genes across cancer lineages are CYBB, FCGR2B, and PPM1M. Each is linked with TWF2 in more than 8 cancer types. Because this analysis shows association rather than direction, both TWF2-to-partner and partner-to-TWF2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TWF2 versus CYBB in OV, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TWF2→partner) and Y-score (partner→TWF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CYBB →	+1.073	+0.254	.009	.004	3	9
GBM	FCGR2B →	+1.377	+0.280	<.001	<.001	3	9
HNSC	PPM1M →	+0.791	+0.314	<.001	<.001	3	9
LSCC	CXorf21 →	+0.818	+0.311	<.001	<.001	3	8
GBM	FCGR2A →	+1.295	+0.347	<.001	<.001	3	8
GBM	VSIG4 →	+1.318	+0.278	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,668 associations by consensus.

TWF2 vs CYBB — OV

Explore this scatter interactively →