TWF2

Across TCGA patient cohorts, TWF2 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TWF2-associated genes across cancer lineages are DC, Monocytes, and MEP. Each is linked with TWF2 in more than 1 cancer types. Because this analysis shows association rather than direction, both TWF2-to-partner and partner-to-TWF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DC grouped by TWF2-low versus TWF2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TWF2→partner) and Y-score (partner→TWF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	DC →	+0.027	+3.234	.014	.009	3	2
COAD	Monocytes →	+0.035	+5.149	<.001	.036	3	1
UCEC	MEP →	+0.043	+2.839	.004	.035	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

DC by TWF2 expression — UCEC

Explore this box plot interactively →