TWF2

Across TCGA cell cohorts, TWF2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,433 significant associations in total. BONE shows the largest number of these associations.

The most reproducible TWF2-associated GO terms across cancer lineages are Regulation of microvillus length, Actin filament depolymerization, and Protein depolymerization. Each is linked with TWF2 in more than 16 cancer types. Because this analysis shows association rather than direction, both TWF2-to-partner and partner-to-TWF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of microvillus length grouped by TWF2-low versus TWF2-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TWF2→partner) and Y-score (partner→TWF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Regulation of microvillus length →	+0.227	+0.780	<.001	<.001	3	17
LUNG_NSCLC_LUSC	Actin filament depolymerization →	+0.213	+1.097	.004	.005	3	16
BREAST	Protein depolymerization →	+0.103	+1.201	<.001	<.001	3	14
LIVER	Positive regulation of lamellipodium assembly →	+0.160	+1.343	<.001	.001	3	14
BONE	Barbed-end actin filament capping →	+0.339	+0.960	<.001	<.001	3	12
LUNG_NSCLC_LUAD	Regulation of lamellipodium assembly →	+0.126	+0.847	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,433 associations by consensus.

Regulation of microvillus length by TWF2 expression — BLOOD_Lymphoma

Explore this box plot interactively →