TWF2

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, TWF2 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TWF2-associated genes across cancer lineages are GSG1L2. Each is linked with TWF2 in more than 1 cancer types. Because this analysis shows association rather than direction, both TWF2-to-partner and partner-to-TWF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GSG1L2 grouped by TWF2-low versus TWF2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TWF2→partner) and Y-score (partner→TWF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEGSG1L2 →+0.016+4.437<.001.00431
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

GSG1L2 by TWF2 expression — LARGE_INTESTINE

Box plot of GSG1L2 in TWF2-low vs TWF2-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration