TUT1

Across TCGA patient cohorts, TUT1 mutation is significantly associated with the RNA expression of many other genes, with 3,566 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TUT1-associated genes across cancer lineages are RNU6-709P, NTAN1, and FCF1P6. Each is linked with TUT1 in more than 2 cancer types. Because this analysis shows association rather than direction, both TUT1-to-partner and partner-to-TUT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-709P grouped by TUT1-low versus TUT1-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TUT1→partner) and Y-score (partner→TUT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RNU6-709P →	+0.189	+4.455	.001	.005	3	3
UCEC	NTAN1 →	+0.402	+2.119	<.001	.002	3	3
UCEC	FCF1P6 →	+0.107	+1.424	.009	.002	3	3
STAD	BNIP3P41 →	+0.042	+3.450	.006	.008	3	3
BLCA	LINC02751 →	+0.124	+3.054	.008	.004	3	2
BLCA	LINC02348 →	+0.180	+3.219	.003	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,566 associations by consensus.

RNU6-709P by TUT1 expression — BLCA

Explore this box plot interactively →