TUSC3

Across TCGA patient cohorts, TUSC3 protein abundance is significantly associated with the RNA expression of many other genes, with 15,871 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TUSC3-associated genes across cancer lineages are IL27RA, PPM1AP1, and LINC02361. Each is linked with TUSC3 in more than 2 cancer types. Because this analysis shows association rather than direction, both TUSC3-to-partner and partner-to-TUSC3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TUSC3 versus IL27RA in LUAD, with a Pearson correlation of -0.54.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TUSC3→partner) and Y-score (partner→TUSC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	IL27RA →	-1.154	-0.830	<.001	.002	3	3
UCEC	PPM1AP1 →	+0.636	+0.825	.003	<.001	3	3
HNSC	LINC02361 →	-0.601	-0.376	.003	.006	3	3
LUAD	PLS3 →	-1.186	-0.857	<.001	.003	3	2
BRCA	DNAJA3 →	-0.504	-0.780	<.001	<.001	3	2
UCEC	STX4 →	-0.625	-0.555	.002	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,871 associations by consensus.

TUSC3 vs IL27RA — LUAD

Explore this scatter interactively →