TUSC3

Across TCGA cell cohorts, TUSC3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,230 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TUSC3-associated GO terms across cancer lineages are Regulation of syncytium formation by plasma membrane fusion, ERAD pathway, and Cytoplasmic translation. Each is linked with TUSC3 in more than 10 cancer types. Because this analysis shows association rather than direction, both TUSC3-to-partner and partner-to-TUSC3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of syncytium formation by plasma membrane fusion grouped by TUSC3-low versus TUSC3-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TUSC3→partner) and Y-score (partner→TUSC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Regulation of syncytium formation by plasma membrane fusion →	+0.112	+2.811	<.001	.001	3	11
STOMACH	ERAD pathway →	+0.056	+1.906	.001	.007	3	11
UPPER_AERODIGESTIVE_TRACT	Cytoplasmic translation →	+0.099	+3.093	.002	.001	3	10
BLOOD_Lymphoma	Endoplasmic reticulum to cytosol transport →	+0.116	+1.281	<.001	<.001	3	10
STOMACH	Viral life cycle →	+0.085	+3.238	.004	.001	3	10
BLOOD_Lymphoma	Retrograde protein transport, ER to cytosol →	+0.116	+1.281	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,230 associations by consensus.

Regulation of syncytium formation by plasma membrane fusion by TUSC3 expression — OESOPHAGUS

Explore this box plot interactively →