TUSC2

Across TCGA patient cohorts, TUSC2 protein abundance is significantly associated with the RNA expression of many other genes, with 10,066 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TUSC2-associated genes across cancer lineages are MIR4446, PIGM, and MPHOSPH9. Each is linked with TUSC2 in more than 3 cancer types. Because this analysis shows association rather than direction, both TUSC2-to-partner and partner-to-TUSC2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TUSC2 versus MIR4446 in LSCC, with a Pearson correlation of 0.32.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TUSC2→partner) and Y-score (partner→TUSC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	MIR4446 →	+1.228	+0.198	<.001	<.001	3	4
LSCC	PIGM →	-0.493	-0.246	.001	.001	3	3
LSCC	MPHOSPH9 →	-0.415	-0.233	.007	.001	2	4
LSCC	CSNK2A2 →	-0.367	-0.165	<.001	.003	3	3
GBM	MTUS2 →	+0.980	+0.628	<.001	<.001	3	3
OV	LSM2 →	-0.605	-0.386	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,066 associations by consensus.

TUSC2 vs MIR4446 — LSCC

Explore this scatter interactively →