TUSC2

Across TCGA cell cohorts, TUSC2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,652 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TUSC2-associated GO terms across cancer lineages are Spliceosomal tri-snRNP complex assembly, rRNA pseudouridine synthesis, and Peptidyl-methionine modification. Each is linked with TUSC2 in more than 11 cancer types. Because this analysis shows association rather than direction, both TUSC2-to-partner and partner-to-TUSC2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Spliceosomal tri-snRNP complex assembly grouped by TUSC2-low versus TUSC2-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TUSC2→partner) and Y-score (partner→TUSC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Spliceosomal tri-snRNP complex assembly →	+0.109	+1.041	<.001	.001	3	12
BLOOD_Lymphoma	rRNA pseudouridine synthesis →	+0.087	+0.619	<.001	<.001	3	12
BONE	Peptidyl-methionine modification →	+0.189	+0.638	<.001	<.001	3	12
SKIN	Mitochondrial potassium ion transmembrane transport →	+0.120	+0.641	<.001	<.001	3	10
PANCREAS	Mitochondrial mRNA catabolic process →	+0.105	+0.631	.003	.002	3	10
BLOOD_Lymphoma	Nucleosome disassembly →	+0.100	+0.544	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,652 associations by consensus.

Spliceosomal tri-snRNP complex assembly by TUSC2 expression — BLOOD_Myeloma

Explore this box plot interactively →