TULP4

Across TCGA patient cohorts, TULP4 mutation is significantly associated with the RNA expression of many other genes, with 6,115 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TULP4-associated genes across cancer lineages are LARP1B, MAPK1, and YWHAE. Each is linked with TULP4 in more than 4 cancer types. Because this analysis shows association rather than direction, both TULP4-to-partner and partner-to-TULP4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LARP1B grouped by TULP4-low versus TULP4-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TULP4→partner) and Y-score (partner→TULP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LARP1B →	+0.416	+1.455	<.001	<.001	3	5
UCEC	MAPK1 →	+0.400	+2.102	<.001	<.001	3	5
STAD	YWHAE →	+0.445	+3.087	.001	<.001	3	4
COAD	EIF5A →	+0.434	+1.926	<.001	.008	3	4
COAD	RNF138 →	+0.554	+2.242	<.001	.005	3	4
COAD	PLK4 →	+0.464	+1.861	.001	.005	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,115 associations by consensus.

LARP1B by TULP4 expression — UCEC

Explore this box plot interactively →