TULP4

Across TCGA cell cohorts, TULP4 mutation is significantly associated with the RNA expression of many other genes, with 401 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TULP4-associated genes across cancer lineages are MRPL18, BHLHE23, and RAB28. Each is linked with TULP4 in more than 3 cancer types. Because this analysis shows association rather than direction, both TULP4-to-partner and partner-to-TULP4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MRPL18 grouped by TULP4-low versus TULP4-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TULP4→partner) and Y-score (partner→TULP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	MRPL18 →	+0.463	+3.502	<.001	.001	2	4
BLOOD_Leukemia	BHLHE23 →	+1.659	+2.954	<.001	.005	3	2
BLOOD_Leukemia	RAB28 →	+0.721	+3.169	.001	.008	3	2
BLOOD_Leukemia	IQCF1 →	+0.073	+2.769	<.001	.003	3	2
LARGE_INTESTINE	DTWD1 →	+0.660	+2.700	<.001	.001	3	2
LARGE_INTESTINE	NEIL3 →	+0.550	+1.850	.006	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 401 associations by consensus.

MRPL18 by TULP4 expression — SKIN

Explore this box plot interactively →