Across TCGA pan-cancer cohorts, TULP3P1 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of TULP3P1’s most consistent transcriptional readouts.
The strongest signal is observed in pancreatic adenocarcinoma (PAAD), where TULP3P1 RNA is repressed in tumor relative to normal tissue. In most cancer types TULP3P1 is over-expressed in tumor, although a few such as PAAD show the opposite, repressed pattern.
PAAD, THCA, and LUSC are the cancer types where TULP3P1 tumor–normal differential expression is most reproducible.