TULP2

Across TCGA cell cohorts, TULP2 mutation is significantly associated with the RNA expression of many other genes, with 279 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TULP2-associated genes across cancer lineages are FGF21, TFR2, and GPR63. Each is linked with TULP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both TULP2-to-partner and partner-to-TULP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FGF21 grouped by TULP2-low versus TULP2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TULP2→partner) and Y-score (partner→TULP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	FGF21 →	+0.287	+3.392	.008	.006	3	1
LARGE_INTESTINE	TFR2 →	+1.356	+3.212	.001	.006	3	1
LARGE_INTESTINE	GPR63 →	+0.968	+3.212	<.001	.006	3	1
LARGE_INTESTINE	WRAP73 →	+0.527	+3.212	.007	.006	3	1
LARGE_INTESTINE	PTCH2 →	+0.331	+3.212	.004	.006	3	1
LARGE_INTESTINE	KCNJ5 →	+0.580	+3.485	.002	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 279 associations by consensus.

FGF21 by TULP2 expression — LARGE_INTESTINE

Explore this box plot interactively →