TUG1

Across TCGA patient cohorts, TUG1 protein abundance is significantly associated with the RNA expression of many other genes, with 289 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible TUG1-associated genes across cancer lineages are NALCN, LYRM1, and POLR2C. Each is linked with TUG1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TUG1-to-partner and partner-to-TUG1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TUG1 versus NALCN in LUAD, with a Pearson correlation of -0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TUG1→partner) and Y-score (partner→TUG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	NALCN →	-0.759	-0.690	<.001	<.001	3	1
LUAD	LYRM1 →	-0.888	-0.856	<.001	<.001	3	1
LUAD	POLR2C →	-0.766	-0.621	<.001	.009	3	1
LUAD	CDIPT →	-0.623	-0.862	<.001	.001	3	1
LUAD	KAT8 →	-0.597	-0.711	.002	.008	3	1
LUAD	AQP9 →	+0.927	+0.645	.005	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 289 associations by consensus.

TUG1 vs NALCN — LUAD

Explore this scatter interactively →